Rothamsted Research in Hertfordshire houses the Molecular Diagnostics laboratory for CHAP. Here, The Centre is able to determine the mechanisms of insect, pathogen and weed resistance to control agents, as well as develop diagnostic techniques that can be used in the field for rapid pest-strain identification.
Why is there a need
This asset will create a national capability for resistance and virulence management utilising facilities and capability located at Rothamsted (lead) and Fera. Rothamsted will undertake early-stage diagnostic development to identify the mutations which underlie resistance and virulence that lead to failure to control pests, weeds and pathogens. Fera will develop and validate existing and newly developed diagnostic methods for high-throughput, real-time laboratory services or in-field monitoring, which will be delivered to the industry to support timely advice to prevent inappropriate pesticide use. Outputs will also be utilised in Asset 1 to extend the in-field surveillance and modelling services to growers.
What is the Asset
Our facilities are stocked with high-tech lab equipment (see Figure 1 for more details) that allows the detection of changes in the genetic profiles of pests that could account for their tolerance to specific control agents. As such, we are able to track the development and/or migration of resistant pest strains in the UK via field samples sent to us by research institutes, farmers or industrial clients. Through the characterisation of genetic features in a pest that correlate with higher rates of resistance to a pesticide, additional partners in CFACS will be able to perform rapid in-field diagnostic tests to inform clients of the particular pest strains present in their fields, allowing efficient, more cost-effective treatment plans to be formulated before large-scale crop destruction has occurred.
How it can help the agricultural sector
The work conducted in this asset at Rothamsted can provide extremely beneficial information to a wide range of researchers and organisations in the agricultural sector: whether you are an agrichemical company looking to investigate the possible development of pest resistance to your product, an academic institute seeking to incorporate some of our expertise and facilities into your next grant proposal related to agricultural pests, or a plant breeder curious as to why your once tolerant crop has suddenly become susceptible to a particular pest, we can assist you. By sending us your samples, The Centre can apply its professional expertise and specialised facilities to answer your questions, allowing you to focus on other aspects of your business or research.
Asset 6 is now up-and-running at Rothamsted Research, and we look forward to supporting you and your research or breeding goals in the near future, whether you are an academic, company
To receive more information on this asset, book a tour of our facilities or discuss a potential collaboration with us, please contact:
Kirsty McInnes (firstname.lastname@example.org; +44 (0) 1582 938 176)
Andrew Spencer (email@example.com; +44 (0) 1582 938 312)
Linda Field (firstname.lastname@example.org; +44 (0) 01582 938 355)